Sentence examples for initiation of coordinated from inspiring English sources

In the presence of prodifferentiation signals, Myc levels are decreased, which leads to activation of Miz-1 bound differentiation genes and results in initiation of coordinated differentiation program.

Because all epidemiology-trained veterinarians were assigned to regional outbreak containment at multiple foci, initiation of coordinated epidemiologic investigation in the farms was delayed by up to 10 days.

Previous exposure to (often incomplete) ART was significantly associated with virologic failure, indicating that short courses of unsupervised ART prior to the initiation of coordinated long-term treatment programs may be counterproductive as they may lead to the rapid development of drug resistance.

Nevertheless, the combined employment of various imaging techniques together with the right kind of accompanying studies in vitro will certainly provide a deepening understanding of the complex cellular choreography that is required for the initiation of a coordinate and appropriate immune response.

According to the generally accepted model, the initiation of asymmetry is coordinated by nodal cilia, which create leftward flow.

Recent years have seen the initiation of an internationally coordinated programme to create ES cells carrying conditional null alleles for all protein-coding genes, and this will be a valuable resource for the research community (7, 8).

Using three-color single-molecule imaging in vitro we revealed how the dynamic associations of Arp2/3 complex with mother filament and WASP are temporally coordinated with initiation of daughter filament growth.

The Mediator complex also regulates the release of hindered PolII, enhances the re-initiation and coordinates RNA capping, splicing and polyadenylation (Borggrefe and Yue 2011).

In this case, DnaA stimulates the expression of a master regulator of cell cycle progression, gcrA, which in turn activates multiple genes, including those involved in chromosome replication and segregation, coordinating the initiation of chromosome replication and cell cycle progression.

In contrast, LexA is a master regulator of genes that is involved in DNA damage and the SOS response, and it has a role in coordinating the initiation of sporulation when the cell is exposed to DNA damage.

Additionally, chemotactic factors coordinate the initiation of podosomes by activating WASP, which is recruited to the extending protrusion and to adhesion sites in a complex with WIP, leading to actin polymerisation at the leading edge and formation of actin cores in podosomes (Fig. 6A).