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Constructing indexes which measure factors that may predict smoking initiation is essential for planning prevention programs.
Since delamination is a major failure mode of layered composites, predicting its initiation is essential for the design of composite structures.
Activated translation initiation is essential for the malignant breast cancer phenotype.
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Formation of eIF4F complexes also depends upon the presence of active eIF4E which, while it is the least abundant of the translation initiation factors, is essential for binding the pre-initiation complex to the cap structure.
The eukaryotic initiation factor eIF4E is essential for cap-dependent initiation of translation in eukaryotes.
The eukaryotic initiation factor eIF4E is essential for cap-dependent initiation of translation in eukaryotes and is considered to be the rate-limiting factor of protein synthesis.
eIF3 is a translation initiation factor that is essential for the interaction between the 43S pre-initiation complex and the mRNA transcript [ 30], whereas the CSN complex is an isopeptidase best characterized by its ability to de-NEDDylate the cullin subunit present in the CRL (Cullin-RING-Ligases) family of E3 ubiquitin ligases [ 31].
IF1 could stimulate IF2 and IF3 activities and act as a protein factor for the stabilization of the initiation complex that is essential for cell viability [59].
Beclin1 has a role in the initiation step and is essential for the formation of the autophagosome.
Hence, a comprehensive understanding of the multifaceted functions of MAPK pathway components in tumor initiation and progression is essential for the improvement of cancer therapy.
eIF3D (eukaryotic translation initiation factor 3 subunit D) is one member of the eIF3 (eukaryotic translation initiation factor 3) family, which is essential for initiation of protein synthesis in eukaryotic cells.
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