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Internal initiation is a 5′-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates.
After initiation engaged RNAPII molecules come under the control of negative factors including NELF and DSIF that limit the elongation potential of the polymerases and trap them in promoter proximal positions [1], [2], [3].
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Room initiation Interviewees engaged in multiple activities to obtain a studio-style classroom.
Lacking a promoter, they undergo relatively infrequent transcription initiation but, once engaged, possibly by virtue of a resemblance to the transcription bubble, their circular topology permits transcription around the template many times, a process termed rolling circle transcription, or RCT (Fig. 1A).
Indeed, improper functioning of proteins engaged in initiation, elongation or replication control manifest as a mutator phenotype.
Meanwhile, macromolecule biosynthetic and metabolic process is also prominent feature in sepsis; it is related to activation and release of bacterial endotoxin, which is a macromolecule engaged in initiation of cytokine cascade [ 60].
Taken together, a Pol II initiation complex can engage in Lsh−/− and WT cells, at hyper or hypomethylated TSS regions; however, Pol II binding at the gene body is only associated with hypomethylated HoxC6 and HoxC8 genes.
ER stress has recently been identified as another major pathway engaged in the initiation of apoptosis [ 18].
We found differences between GPs engaged and those not engaged in insulin initiation in attitude, subjective norm and perceived behavioural control regarding insulin initiation.
When listening to preferred musical pieces, their eye tracking movements were normalized in that they engaged the target concurrent with reach initiation and disengaged quickly after the target was grasped.
During exponential growth in rich media, deletion of TIF4631 reduces proliferation and global translation initiation rates, and decreases the fraction of messages engaged in translation from genes that encode small proteins from transcripts with long 3' poly(A) tails.
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