Sentence examples for initiation component from inspiring English sources

In turn, PrkC phosphorylates the essential translational initiation component elongation factor G (EF-G).

In this report, we investigated which domain of mIgG resulted in the low or none requirements on mechanical forces for IgG-BCRs compared to the case of IgM-BCRs since both of these two forms of BCRs use the same signaling initiation component, Igα and Igβ heterodimer.

Thus, it is likely that the requirements for initiation components have not changed, and that the initiation mass is not significantly changed.

Stress granules contain translation initiation components and a diverse array of mRNA binding proteins, but the exact composition can vary depending upon the stress [5] [12].

Initiation of translation in eukaryotes is thought to be rate limiting [53] and overexpression of initiation components, for example the initiation factor elF4E, occurs frequently in human cancers [54].

Analysis examined 10 initiation components separately, then together, comparing women who underwent all rites, some rites and no rites.

For instance, ERK1/2 activation affects multiple translation initiation components including S6K, p90 RSK, MNK and 4E-BP1, amothersheRouxRoux and Blenis, 2004).

The observed downregulation of rRNA synthesis is not, then, an indirect effect of decreased Pol II transcription leading to reduced availability of Pol I transcription initiation components.

It has been observed that in proliferating cells, minimal activity of p53 can lead to basal expression of some of its target genes, such as p21 (Tang et al., 1998), through mechanisms involving basal promoter-specific recruitment of transcription initiation components (Espinosa and Emerson, 2001; Espinosa et al., 2003).

Reviewer #2: The major concern I have with this paper is that CDK1 has been shown recently to directly phosphorylate two master regulators of protein synthesis, namely 4E-BP1 (Shuda PNAS, 2015) and eIF4GI (Dobrokov et al. Mol Cell Biol, 2014; 34:439-451), and that CDK1 phosphorylation of these two translation initiation components dramatically affects their translational activity.

The major concern I have with this paper is that CDK1 has been shown recently to directly phosphorylate two master regulators of protein synthesis, namely 4E-BP1 (Shuda PNAS, 2015) and eIF4GI (Dobrokov et al. Mol Cell Biol, 2014; 34:439-451), and that CDK1 phosphorylation of these two translation initiation components dramatically affects their translational activity.