Sentence examples for initiation at the first from inspiring English sources

Their sizes are consistent with alternative initiation at the first three AUGs of C sequence.

Only one product is synthesized from each mRNA analyzed and these products are always generated from translation initiation at the first AUG present at their respective sequences.

Determine TB-LAM could close this treatment gap for the patients who have the lowest CD4 cell counts and highest mortality risk, permitting TB treatment initiation at the first clinic visit.

For both PpRPOTmp1 and PpRPOTmp2, translation initiation at the first of two in-frame AUG start codons was found to compose a polypeptide with N-terminal plastidial targeting properties, whereas initiation at the downstream AUG gave rise to a mitochondrial protein (Richter et al. 2002).

Whereas two of the alternative AUG codons appear incompetent for translation initiation, we detected strong initiation at the third AUG, which is followed by one AAA codon and a UAG stop codon.

In estimating our results, we had in mind the first initiation codon, which is thought to have more favorable flanking sequences for initiation of protein synthesis, although use of leaky scanning mechanism could be the reason of initiation at the second AUG codon (21 ).

Mutations in various initiation factors are known that elevate the UUG AUG ratio and restore translation of mutant his4-301 mRNA, which lacks the AUG start codon, by enabling initiation at the third, UUG codon, thereby suppressing histidine auxotrophy and conferring a Sui− (Suppressor of initiation codon mutation) phenotype.

It is expected that this uORF would drastically inhibit translation from the first SPG4 AUG, while allowing re-initiation at the second AUG that has a G in position +4 and is located at a sufficient distance from the stop codon of the uORF.

The mutation that affected the initiation codon, c.1A>G (p.Met1?), for B3GALT6 resulted in a lower molecular weight of the recombinant protein than that of the wild-type protein with the deletion of 41 amino acids at the N-terminus, which indicated a shift in translation at the initiation codon at the second ATG [ 70].

From this "ankle-crossing" time point, the middle of gait initiation was set at the first toe off (exactly 45%) and using a pre-trigger, the total cycle was defined from 0%.

Initiation of translation at the first AUG codon leads to synthesis of a NSm GN GC precursor that contains a signal sequence upstream of NSm, which allows for translocation of the polyprotein into the endoplasmic reticulum.