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Curved lateral faces of lamellar polymer crystals have previously been described mathematically using a model of initiation and spreading of molecular steps on the growth surface.
Lowndes et al. (2007) conducted an experimental and computational study to characterize the initiation and spreading of the fires along the upper and lower surfaces of a conveyor belt mounted within a ventilated full-scale experimental fire test gallery.
The initiation and spreading of DNA methylation at the Oct-4 regulatory region is therefore dependent on de novo methyltransferases and cannot be achieved by the "maintenance" enzyme Dnmt1 alone.
This model is supported by the results of bisulfite DNA sequencing (Figures S16 and S21) and methylation-sensitive restriction analyses (Figure 5D), which reveal an involvement of the SET domain and MBDL in initiation and spreading, respectively, of DNA methylation at the Rb locus.
X-chromosome inactivation (XCI), the dosage compensation process that equalizes X-linked gene expression between sexes, has mostly been studied in the mouse, where the central role for the non-coding RNA Xist in the initiation and spreading of the process was demonstrated.
While brain complexity, with its interconnected neuronal loops, complicates the in vivo analysis of pathophysiological initiation and spreading mechanisms, we were able for the first time to evaluate the distant effects of local cortical β-amyloid deposits on neuronal subcompartments and networks in μFD-based reconstructed cortico-hippocampal networks.
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Currently, it is believed that only this small fraction of cancer cells is able to drive tumor initiation, proliferation, and spreading [ 6].
The proposed system is expected to assist forest researchers, forest service officials and land managers to evaluate fuel hazard and assess the potential for initiation and spread of wildfires in Aleppo and Calabrian pine forests in Greece.
Crown Fire Initiation and Spread (CFIS) simulations indicated that these changes in understory structure would only decrease the behavior of a potential wildfire when occurring in low or moderate weather conditions.
This triggered the initiation and spread of filamentous tau deposition in the brain of these recipient animals.
The use of GFP transgenic lines that show stochastic frequencies of silencing initiation and spread enabled us to investigate effects that light may have on silencing events.
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