Sentence examples for initiation ability from inspiring English sources

Notably, TAZ is also required for the maintenance of self-renewal and tumor initiation ability of oral cancer stem cells (Li et al., 2015b).

It is considered that complexation of potassium cation with the ProHEMA molecule increased the nucleophilicity of the oxonium anion to increase the initiation ability.

Formation of spheroid bodies and in vivo tumor initiation ability were demonstrated in CD44+ cells of 4 cell lines.

These observations are consistent with the notion that CSCs are unique in their metastatic potential as well as tumor initiation ability.

Our study does not show that all CD44+ cells are bona fide CSC, however, we propose that CD44 could be a marker of tumor initiation ability in some lung cancer cells.

It now remains to determine whether p53 could modify the post-transcriptional steps of ribosome biogenesis, in particular the level of rRNA methylation Altogether our results show that breast cancer cells with enhanced aggressivity display profound alterations in ribosome biogenesis resulting in the modification of translational initiation ability of the ribosomes.

Previously, we demonstrated that MYC-driven hepatic tumors have a strong side population cell population that is enriched for cancer stem cells with tumor-initiation ability.

Furthermore, after incubation in medium with serum for 6 days, the enhanced tumor-initiation ability of T24 sphere cells was compromised (five mice per group), suggesting that T24 sphere cells might possess differentiation potential (Supplementary Figures S1b d).

After transplantation in WT mice, these cells developed primary and metastatic mammary tumors that resembled the parent tumor and primary tumors derived from transplantation with lung cells, thus linking metastasis from PyMT-induced primary breast carcinoma to a subset of cells with tumor-initiation ability.

However, increased EMT features induced by MSC-CM was not associated with increased secondary mammosphere formation, which is considered a more rigorous test of self-renewal in vitro [ 7], and here, pretreating SUM149 cells with MSC-CM decreased the tumor-initiation ability of cancer cells in vivo.

Thus the differing tumor-initiation abilities of SP and non-SP cells are most likely due to an artifact of Hoechst 33342 toxicity, rather than due to intrinsic stem-cell properties [ 32].