In a randomized, double-blind, parallel-group, active-controlled fashion, one group of patients continues to receive tiotropium, salmeterol and fluticasone, while the second group initiates stepwise withdrawal of fluticasone.
Treatments were initiated stepwise according to clinician preference at the time, and were recorded as exclusion diet (i.e. novel or hydrolysed protein diet fed exclusively), antimicrobial therapy (metronidazole), and/or immunosuppressive therapy (prednisolone, azathioprine, and/or cyclosporine).
The commercial importance is due to the fact that it initiates the stepwise dephosphorylation of phytic acid, the primary storage form of phosphorus in most seeds and cereal grains, which is about 50 80% of the total phosphorous content in plant tissues [1 3].
The third stage of the anodization process is initiated, applying a stepwise current-limited re-anodization procedure under a galvanostatic regime in the same electrolyte.
In vitro, module 1 was reconstituted stepwise, initiated by Rpn11 Rpn8 heterodimerization.
In this work, we report the central role of MYC in initiating and sustaining a stepwise cell reprogramming process of mammary epithelial cells toward a stem cell-like condition, favoring tumor initiation and progression.
It is a stepwise method initiated by an analysis of the problem context, followed by identification of options, assessment, and analysis of the options' impacts, and finally sensitivity and value analysis (Bana e Costa et al. 2004).
When elevated ICP or brain herniation occurs, the so-called emergency neurological life support (ENLS) should be initiated, which includes the stepwise management of these events [ 63].
These results indicate that NuA4 recruitment at DNA breaks occurs through a stepwise mechanism, initiated a phospho-dependent interaction with MRX, followed by spreading through DNA end resection where it regulates RPA dynamics.
Establishment of the tumor microenvironment is a stepwise process initiated by tumor hypoxia and ischemia 17 and subsequently marked by interstitial and cellular edema, a chronic inflammatory infiltrate, neovascularization, and tissue repair 16.
