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Initiating protocol, @oha_hawaii Ka Pouhana, Kamanaʻopono Crabbe is heard by Hōkūleʻa and the rows of people aroun… https://t.co/1Lj1xE3gRl pic.twitter.com//t.co/1Lj1xE3gRl
Treatment-emergent adverse events (AEs) were defined as events that had newly occurred or had worsened after initiating protocol treatment.
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ASAP sessions were used to prevent premature termination (investigator initiated protocol violation) and dropping out (withdrawal of consent).
This is particularly important as patients were expected to have active disease at the time they initiated protocol treatment.
A lactate threshold ≥4 mmol/L has been used to initiate protocol-based resuscitation [20, 21].
A lactate threshold ≥4 mmol/L has been used to initiate protocol-based resuscitation [ 20, 21].
The process of registration of misoprostol for PAC was initiated, protocols for MPAC provision were developed and disseminated, and training of MPAC providers was begun.
All sites except one were in the field with the intervention by early 2012, with one site initiating the protocol in summer 2012.
However, some limitations of the study create difficulties in initiating this protocol in our institution.
Prior to initiating the protocol, a preliminary evaluation as detailed below will be performed.
They recommend initiating this protocol as soon as hypoperfusion is recognized and it should not be delayed pending ICU admission.
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