Sentence examples for initiating compound from inspiring English sources

On the other hand, no evidence is available yet to show that BHT would enhance tumor development in animals treated with subcarcinogenic doses of an initiating compound.

Nerves innervating the body muscle walls were cut near the ventral ganglion and stimulated using a suction electrode and isolated pulse stimulator Digitimer DS2A (constant current modification), with a current double that needed to initiate a compound response.

In order to find new chemical scaffolds, we initiated a compound screen using our in-house kinase inhibitor collection and subjected them to a cell-based of Plasmodium falciparum proliferation assay We envisioned that the hits arising from this screen can be rapidly optimized by leveraging our past experiences with these compounds series in alternative target-classes/indications.

Although all xenoestrogens shared activation via the PI3K pathway, PI3K inhibitors could not lower DDE- or coumesterol-mediated ERK phosphorylation levels until ≥6 min, so perhaps progression to this level of signaling took variable amounts of time depending upon the compound initiating the response.

Women initiated on compounded BHRT experienced significant reductions in moderate to severe mood symptoms within 3 to 6 months.

During this timeframe, no woman initiated on compounded BHRT experienced a myocardial infarction (MI) or breast cancer.

From this cohort of 296 women initiated on compounded BHRT, 62 (21%) had documented follow-up regarding myocardial infarction and breast cancer.

These radicals can react with organic compounds, initiating their degradation (Suslick et al. 1986; Yim et al. 2002).

Additionally, we report on the cyto- and acute toxicity profiles of the best extracts and fractions of the two plants, thereby initiating a novel lead compound discovery endeavour.

Src inhibitors might have an important role to play in inhibiting osteoclast activation, and several lead compounds are initiating their clinical evaluation alone and in combination with other relevant treatments.

These results indicate that the direct activation of mitoKATP by PD153035 can explain cardioprotection by this compound, although cardioprotection may also involve increases of this channel's activity by AKT-independent intracellular signaling events initiated by this compound's inhibitory effect on EGF receptor tyrosine kinase.