Sentence examples for initiating capability of from inspiring English sources

Together, these data demonstrate that Six1 overexpression in luminal MCF7 breast cancer cells significantly increases the tumor initiating capability of these cells.

In vivo tumour initiating capability of siRNA treated cells was assessed by orthotopic mammary fat pad transplantation and tail vein injections of BT474 and MDA-MB-231 cell lines, respectively.

The initiating capability of SA-EITC in various monomer formulations was verified by monitoring bulk polymerization kinetics through the use of Fourier transform infrared (FTIR) spectroscopy (Nicolet Instrument Corporation, Madison, WI, USA).

The tumour-initiating capability of these tumour stem-like cells was tested in serial brain tumour transplantation experiments using SCID mice.

Therefore, according to our results, the increased tumor-initiating capability of the cycling hypoxia-selected subpopulations is in accordance with the increased ability to grow as spherical colonies in culture.

The in vivo tumor-initiating capability of the 10AT-Her2 celineine in comparison to control 10AT-Neo cells was analyzed by formation of tumor xenografts in NIH III athymic nude mice.

Our in vivo data are limited to the mouse-recipient strain, which we have been using for this study (Nod/Scid mice), and we are aware that the use of different mouse recipients can have an impact on the tumour-initiating capability of injected cells (Quintana et al, 2008).

To confirm that the sphere-forming cells exhibit greater tumor initiating capability, NOD/SCID mice were transplanted with varying amounts of the PLC/PRF/5 sphere-forming cells ranging from the amount that is unable to initiate tumor growth to the amount that always initiates tumor formation.

The cancer stem cell theory suggests that a fraction of the cancer cell population is enriched for tumor initiating capability, thus requiring preferential targeting to achieve therapeutic benefits.

We tested the third, sixth and ninth generations of the PLC/PRF/5 sphere-forming cells for their tumor initiating capability.

The results showed that both the tumor initiating capability and phenotypic appearance were similar for the 3th, 6th and 9th generations of sphere-forming cells (Table 1).