Sentence examples for initiating ability of from inspiring English sources

The reduced tumour initiating ability of CD44+CD24neg DT-22 was reproducibly evident at several different cell numbers injected (Fig 3A and B).

Next, to directly test whether overexpression of miR-200c could affect tumor initiating ability of BCSCs in vivo, we performed limiting dilution assay for mammary tumors.

We also found that inhibition of miR-181s leads to a reduction in quantity and tumor initiating ability of EpCAM+AFP+ HepCSCs, suggesting the potential utility of these miRNAs as molecular targets of HepCSC [ 9, 10].

Because of the lack of initiating ability of AAP in liver, we have also investigated early biochemical alterations in liver after various regimens.

It has previously been shown in animal models that the leukaemia-initiating ability of these different CD34/CD38 subpopulations can differ6.

They confirmed that the leukaemia-initiating ability of the cell fractions differed: leukaemia could form from all the cell fractions obtained from a patient, from some of the fractions or from none.

Although several investigators have recently published reports about CD133+ colon cancer cells [3], [12], [26], there were inconsistent data regarding the tumor-initiating ability of CD133+ colon cancer cells.

Seemingly, CD44 overexpression is essential for the anchorage-independent growth, tumor growth and tumor-initiating ability of highly tumorigenic mammary epithelial cells.

Although testing the tumor-initiating or metastasis-initiating ability of CD133+ cells was beyond the scope of our study, our results suggest that these cells display a differential DNA methylation signature.

The reduction in miR-21 expression could be coupled to a decrease in SOX2 expression, loss of tumor-initiating ability of the cells and induction of oligodendrocyte differentiation [ 33].

Although the functions of upregulated genes varied, these results suggested that the factors connected to DNA transcription, transport of substrates, cell proliferation and apoptosis might have a role in the cancer-initiating ability of SP cells.