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Initially, to assess whether LOX expression was required for invasion, we used siRNA to knockdown LOX expression and measured migration of KPC cells through a Matrigel matrix (Supplementary Fig S2A).
It provides guidelines and tools for external assessors to use initially to assess whether hospitals meet the Global Criteria and thus fully comply with the Ten Steps, and then to reassess on a regular basis whether they continue to maintain the required standards.
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It has been designed initially to assess deficit symptoms in schizophrenia.
CBM methodology was initially developed to assess whether interpretation and attentional biases were causal in the development of individual differences such as trait anxiety.
Initially, titles were reviewed to assess whether they met inclusion criteria.
Initially CD4 date was used to assess whether linked records were a genuine match.
Data from two phase 3 studies of eribulin were pooled in analyses initially requested by the European Medicines Agency to assess whether specific patient subgroups, previously treated with an anthracycline and a taxane, benefited from eribulin.
Effective ecosystem conservation requires noticing changes both initially before active management has taken place and later to assess whether an employed conservation strategy is adequate.
Analogous to the uracil nucleotides, we wanted to assess whether the cysteinyl leukotrienes also activate hGPR17-L, initially focusing on LTD4.
To assess whether raptor was a potential GSK3 target, we initially performed in silico analysis for putative GSK3 phosphorylation motifs on raptor.
To assess whether smoking habits would confound the effects of noise on BP, we initially included smoking in the regression model.
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