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Although considered as non-polyreactive initially, subsequent studies indicated that 10E8 possibly needs to bind membrane lipids, especially cholesterol, to mediate neutralization (Huang et al., 2012; Chen et al., 2014; Irimia et al., 2017).
Although the clinical response rate after platinum- and taxane-based chemotherapy is usually high initially, subsequent relapses and repetitive treatments using cytotoxic chemotherapies lead to an acquired resistance to those treatments.
Coagulation tests were carried out in 17 patients and in 8 of them at least one anomaly was detected at presentation; additionally, in two patients who had normal test results initially subsequent tests were found abnormal.
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One subject with ONG had a normal VEP initially but subsequent VEP was abnormal.
When the percentage change in VEGF level from baseline was assessed over time, there was a trend suggesting that the levels dropped initially with subsequent rebound.
Simple unadjusted rates, relative risks and 95% confidence intervals will be obtained initially, with subsequent multiple regression analysis adjusting for paired randomisation and other variables.
Current strategies often use thrombolysis initially with subsequent use of MTDs if thrombolysis is inadequate to recanalize the vessel [ 6, 7].
Although no renal defects were initially reported, subsequent analysis has revealed cystic kidneys in Bbs4 tmices mice (Guo et al., 2011), but polydactyly was not exhibited (Mykytyn et al., 2004; Eichers et al., 2006).
Its response can be characterized by hyperinflammation initially, with a subsequent immunosuppressive phase.
While the structures obtained by hydro-thermal chemical deposition are highly crystalline and grow as nanorods, the microwave-activated reactive sputtering films are initially dense with subsequent increase in porosity, leading to unusual cylindrical structures with hemi-spherical caps.
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CEO of Professional Science Editing for Scientists @ prosciediting.com