Sentence examples for initially responsive from inspiring English sources

The serial collection of solid tumor samples from the same patients has been extremely difficult in the clinical setting, but gastric cancer provides a unique opportunity for this purpose, since it is often initially responsive to chemotherapy and repeated endoscopies may be performed to monitor tumor response to chemotherapy.

Although initially responsive to therapy, indolent non-Hodgkin lymphomas (NHLs) are generally incurable.

In the case of triple negative breast cancer, many are initially responsive to traditional chemotherapeutic agents; however, the likelihood of recurrence is high, typically with a more aggressive, less responsive tumor.

Men with prostate cancer may be initially responsive to androgen receptor (AR) inhibitors, but in some patients, single-cell RNA-seq of individual CTCs detected heterogeneity in the expression of AR gene mutations and activation of non-canonical (β-catenin-independent) Wnt signaling, which may promote invasiveness and malignant progression, thereby contributing to treatment failure [77].

Initially responsive to hormonal ablation therapy, PCA invariably recur and evolve to become lethal androgen-independent (AI) disease.

Although most patients are initially responsive to platinum-based chemotherapy, almost all develop recurrent chemoresistant tumors and succumb to their diseases.

Despite the undoubted benefits that endocrine therapies have brought for breast cancer patients in terms of increased survival, de novo and acquired resistance to such treatments presents a major clinical problem; not all patients with oestrogen-receptor (ER) positive disease benefit and a significant number of initially-responsive patients ultimately relapse on such treatments [ 1].

This suggests that temporally, the amygdala in ASD may be initially as responsive or even hyper-responsive to social cues as compared to that of typically developed individuals.

While larger trees were initially less responsive to thinning, the rate of decrease in the response for subsequent years was greater in smaller trees than larger ones.

These heat maps show that the effect of noise stimulation was to increase the response to noise stimuli selectively in neurons that were initially more responsive to noise than to gratings, as indicated by warm spots above the diagonal in E and lack of warm spots in H.

The effect of grating stimulation was to increase the response to grating stimuli selectively in neurons that were initially more responsive to gratings than to noise, as indicated by warm spots below the diagonal in I, and paucity of warm spots in F, (p<0.001 for all comparisons E vs H, F vs I, Chi-square).