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Simulator technology was initially proven to be a useful teaching tool in aviation; nowadays, it has great potential for training [5, 6, 7, 8, 9] and objectively assessing laparoscopic skills [4, 5, 6, 9, 10, 11].
What regulators expect are well-conducted and well-described studies adhering to principles of good clinical practice, which can be scrutinized for evidence of clinical efficacy and which are based on the initially proven principle for the drug.
For this, a commercial package called UDEC was used and the accuracy of UDEC was initially proven by an analytical solution of the reflection and transmission of the incident wave.
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The case initially proved tough to solve.
The conflict initially proves a rather pleasant prospect for Daisy and her four cousins.
Life there initially proves to be lucrative, even though neither outlaw knows Spanish.
The city's angry and unrepentant rebel residents initially proved unwilling to submit to federal authority.
Any hopes that Wales might have had that the absence of Thomas Vermaelen and Jan Vertonghen would weaken the Belgian defence initially proved unfounded.
Banished to the sticks, where a missing snow-colored swan initially proves the only investigative distraction, he finds himself desperate for action.
Poor economic and organizational handling of the restructuring, however, resulted in spiraling health care costs that initially proved difficult to address.
Mr. Hockney, of course, has another reason for displaying the "Great Wall": He welcomes any opportunity to advance his theory on optics, which initially proved so controversial.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com