Sentence examples for initially downregulated upon from inspiring English sources

Fgf4 and Nr0b1 expression was initially downregulated upon switch to 2i/LIF, but reappeared during later time points together with other pluripotency markers.

Again, Bcl-xL protein level was not initially downregulated, but increased at later time points after UVB exposure, similar to cyclin D1 and c-Myc (Fig. 7D).

Aggrecan and brevican were initially downregulated in the lesion and was unchanged in both spinal enlargements [ 105].

Pou5f1 transcripts were present in the mouse zygote and initially downregulated, followed by upregulation at the 8-cell stage.

p53 might initially downregulate Sall2 to support DNA repair and survival, but Sall2 is then necessary to cooperate with p53 to promote apoptosis if irreversible DNA damage occurred.

Group IV contained 128 genes downregulated upon both exposure times, whereas 95 genes of group V exhibited downregulation after 20 min. Finally, group VI had 79 genes that were downregulated upon 60 min exposure.

Therefore, our results point out that DR6 is a novel marker of pDCs and rapidly downregulated upon activation.

In vivo, transcripts repressed upon miR-125b induction are enriched >700% for predicted miR-125b targets normally downregulated upon SC-lineage commitment.

Additionally, 26 genes were significantly downregulated upon SOX11 silencing in Granta 519.

miR-376a was induced between the 8-cell and morula stages, and rapidly downregulated upon blastocyst formation (Fig. 5c).

miRNAs downregulated upon differentiation may serve either as repressors of trophectoderm specification in the pluripotent state, or as active promoters of pluripotency.