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The series was initially directed by Masaaki Ōsumi, who was then replaced by Hayao Miyazaki and Isao Takahata.
The onset of zygotic gene activation is initially directed by stored maternal RNAs and proteins, and most maternal transcripts are replaced by new products of zygotic transcription.
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Opposition was initially directed at the curriculum -- prepared by two yoga practitioners from Los Angeles, where the curriculum is also used in some schools -- which has since been altered to eliminate any language that might be construed as religious.
Adapted from Ethel Lina White's novel The Wheel Spins, it was initially to be directed by Roy William Neill, an American B-movie specialist now best known for the Sherlock Holmes series starring Basil Rathbone and Nigel Bruce.
Interestingly, the film was initially going to be directed by Aronofsky, who ended up making "The Wrestler" instead.
As initially reported, microcapsule assembly was directed by the propensity of the gold nanoparticles to assemble at an oil water droplet interface to form a Pickering emulsion, leading to accumulation of capsule-forming materials and ultimately the formation of a flexible supramolecular nanocomposite skin.
Maintaining a frenzied pace as it recalls the urgent matters of that era, the play, weakly directed by Seth Duerr, is initially exhilarating but eventually limits its chances to examine what made Lyndon run.
Nothing is what it initially seems in a play beautifully directed by Daniel Goldman and exquisitely performed by Trevor White and Alex Austin, which constantly discombobulates the audience as it explores truth and lies, the art of storytelling and how often we only see the things we want to.
After the attack in San Bernardino by US citizen Syed Rizwan Farook and his Pakistani-born wife Tashfeen Malik, investigators from the police, the Department of Homeland Security, and FBI were initially concerned that the attacks were directed by ISIS from overseas.
Cocteau was drawn back to film-making, initially as a screenwriter on Le Baron Fantôme (1943), directed by Serge de Poligny, and L'Éternel Retour (1943), directed by Jean Delannoy.
Initially running for six hours, the play was first directed by Mike Leigh at London's Unity Theatre in 1965.
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