Sentence examples for initially demonstrated by from inspiring English sources

The existence of breast cancer-initiating cells was initially demonstrated by Al-Hajj and colleagues [ 1] using antigen expression, and subsequent studies have employed several methodologies to identify and isolate these cells.

Because of the anatomical proximity of the trachea and the ascending aorta, results could be improved markedly with the ECOM device, as initially demonstrated by Wallace et al. [11].

The importance of Wnt signalling in the control of bone mass was initially demonstrated by the high and low bone mass phenotype caused by loss- and gain-of-function LRP5 mutations, respectively [16].

The applicability of meta-analysis to microarrays was initially demonstrated by [ 4, 5].

The role of TCF7L2 in hormone gene expression was initially demonstrated by our group [ 80].

NSE were initially demonstrated by the high-titre measles vaccine (HTMV) incident.

We initially demonstrated that infection by HSV-1 (F) results in the selective enrichment of cytoplasmic isoform variants lacking exons 5 and 6, and that a novel PMLΔ5&6 variant, PML Ib is expressed during HSV infection.

The importance of imprinted genes for placental and foetal development was initially demonstrated in mice by observations that parthenogenetic embryos (maternal origin, digynic diploid) could show embryonic differentiation but failed to form extraembryonic components [ 6].

This was initially demonstrated for influenza viruses by a simple membrane fusion assay, hemolysis of erythrocytes that occurs only if virus particles containing cleaved HA or HEF are exposed to acidic pH (Formanowski et al., 1990; Huang et al., 1981; Kitame et al., 1982; Lenard and Miller, 1981; Maeda and Ohnishi, 1980; Ohuchi et al., 1982).

The potential of DWI for monitoring disease in the head and neck has been initially demonstrated in an animal model followed by promising results in patients with head and neck squamous cell carcinoma as shown in recent studies.

We and others initially demonstrated that double-strand breaks generated by Cas9/sgRNA ribonucleoprotein complexes can be repaired from a plasmid harboring a DNA template containing homology on both sides flanking the lesion (Chen et al. 2013; Dickinson et al. 2013; Tzur et al. 2013; Kim et al. 2014).