Exact(1)
After initial studies defined the characteristic length of piRNAs to be in the range of 23-32 nucleotides [ 3, 4, 10, 12, 13], larger than that of miRNAs, most studies of piRNAs extracted and analyzed sequence reads whose length was in this range.
Similar(59)
In the initial study defining Ecdysozoa [ 3], rate variation was considered to be the major bias affecting the phylogenetic position of nematodes.
In this chapter, we present a roadmap to structurally characterize a folded RNA, beginning from initial studies to define the overall architecture and leading to high-resolution structural studies.
Both studies defined migratory lingcod as recaptures >8.1 km from the initial tag site.
A decrease of more than 1 in the LV wall motion score at follow-up compared with the initial study was defined as regional wall motion improvement [23].
Of note, our initial studies with ZDON defined incubation times appropriate to inhibit TG2 in a test tube assay (McConoughey et al, 2009).
Initial studies, aimed at defining the kinetics of PI3K/mTOR and canonical Smad signaling in pHLFs during TGF-β1-induced collagen deposition, revealed that Smad signaling was rapid and relatively short-lived with Smad2 phosphorylation peaking within the first hour and declining after 2 h (Fig. 1a).
However, 41% of their cohort were nonresponders who did not achieve at least a PR to initial bortezomib treatment, and this study defined the gap between the final dose of the initial treatment and retreatment as only 60 days.
Initial clues about the role of Pak1 in mammalian cell division came from studies defining regulated phosphorylation of Pak1 in fibroblasts and neuronal cells [ 40, 41].
But different studies define violence differently.
To overcome this problem, the present study defined incident cases either by initial admission or a visit containing a diagnosis of hip fracture.
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