As an initial step of this approach, we concentrate on one class of mobile genetic elements, LTR-retrotransposons, which share a unique structural feature, two long terminal repeats (LTRs) that are longer than 100 bp and play a key role in their transposition.
Among the approaches towards disease modifying treatment of Alzheimer's disease blocking the initial step of the amyloid cascade, Aβ42 generation, has received most attention.
The development of the portal is based on a user-centered approach that involves users directly, beginning with the initial steps of the process.
Finally, the transferability of method was tested in an interlaboratory exchange study as an initial validation step of the approach.
Although the initial step of design using this approach is also calculation of stiffness, elastic time period and different strengths of the structure, it is quite different from the traditional methods as includes direct control of displacements instead of indirect control using ductility coefficients.
An antibiotic-releasing porous polymethylmethacrylate (PMMA) construct was developed to maintain the bony space and prime the wound site in the initial step of a two-stage regenerative medicine approach toward reconstructing significant bony or composite craniofacial tissue defects.
The use of a strategy involving space maintenance as the initial step of a two-stage regenerative medicine approach toward reconstructing significant bony or composite tissue defects in the craniofacial area, preserves the void volume of bony defects and could promote soft tissue healing prior to the subsequent definitive repair.
And all because she make the initial step of DUMPING THEM ON THE PILE.
An additional caveat of our approach is that the initial step of assigning GWAS traits to disease and age-related vs. non-age-related categories introduces some interpretation in the analysis.
