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Initial sputum processing was done within 24 hours.
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Despite optimization of sputum processing 65/73 (89%) of the IGRAs in the validation phase were inconclusive.
All three tests required the same sputum processing cost of $2.15.
The direct consumables cost for sputum processing, inoculation and reading of the susceptibility test were estimated.
We used unselected and consecutively recruited patients, a different population group, and different sputum processing methodology.
Initial sputum smear grade and the number of lung zones involved by tuberculous lesions were greater among patients enrolled in Uganda.
Initial sputum AFB smear was positive in all these patients with treatment failure.
Processing of sputum with subsequent concentration by centrifugation or sedimentation may increase the sensitivity of smear microscopy [ 14], and some investigators have recommended sputum processing and concentration as a global standard [ 15].
Various physical and chemical sputum processing methods have been identified which can improve the sensitivity of microscopy.
The date of initial sputum culture positivity was reported in 1568 patients (68% of the pulmonary TB cases), and anti-tuberculosis therapy was started less than one week after collection of the initial sputum culture in 70%.
The dog's initial sputum sample was negative on AFB staining and M. tuberculosis nucleic acid amplification assay.
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CEO of Professional Science Editing for Scientists @ prosciediting.com