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Samples were obtained at protocol-defined points; initial samples were obtained from diagnostic leukemia cells prior to the start of induction chemotherapy.
The initial samples were obtained 8 days after admission to the ICU and once a week thereafter.
The initial samples were obtained prior to IL-1Ra injection and the second set of samples was obtained a mean four weeks later.
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Blood samples were collected during hospital admission, on day 4 or 5 of hospitalization, and 2 weeks after the initial sample was obtained.
The initial sample was obtained from a commercial company specialising in the supply of publically available data (names and addresses) for use in research.
In general, if an irregular karyotype is detected, it is not possible to conclude that it arose during culture because there is a possibility it was already present in the cells of the individual from whom the initial sample was obtained, as in the YAN3191 cell line.
The first initial fecal samples were obtained at 11 days of life (n = 47, [interquartile, 7 15 days of life]) and the median fecal calprotectin levels were 87 µg/g [interquartile, 35 153 µg/g].
Once a suspected diagnosis of DKA was made, the initial laboratory blood samples were obtained for basal metabolic parameters and complete blood count with differential; urinalysis was performed for blood and urine ketones by both the nitroprusside and enzymatic methods.
Out of the initial 36 patients, oxytocin samples were obtained from 35 patients after 1 week and from 33 after 4 weeks.
All patient bone' marrow samples were obtained at initial diagnosis by the Pediatric Hematology/Oncology Department at Children's Hospital of New Orleans with IRB approval.
All ovarian cancer samples were obtained at initial cytoreductive surgery from patients treated at Duke University Medical Center and the H. Lee Moffitt Cancer Center and Research Institute, who then received platinum-based primary chemotherapy [ 15].
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