Sentence examples for initial mutations that from inspiring English sources

This approach gives scientists the opportunity to spot the initial mutations that accompany the condition, rather than trying to work though possible genetic contributions from maternal and paternal lines.

Could there be a bacteria or virus that triggers the initial mutations that eventually lead to cancer?

Collagen I chains containing mutations that affect initial chain association, such as those in the pro-α1(I), are removed by retrotranslocation of monomeric unfolded mutant collagen chains into the cytosol, followed by ER-associated degradation (ERAD an ATP-dependent ubiquitin-proteasome process that reduces the burden of excess unfolded proteins on the ER [9].

By tracking the evolving organisms and reconstructing the phylogenetic relationship of the surviving lineages we can identify the exact mutations that cause the initial divergence between lineages.

Initial mutations in NEDD1 suggested that residues that are not strongly predicted to adopt an α-helical conformation might provide a binding surface for γ-tubulin.

Initial methods focused on the identification of mutations that disrupt transcription factor binding sites (TFBS) [ 13- 15].

Therefore, mutations that result in increased initial plant host penetration can actually be detrimental to overall pathogen virulence.

However, the types of mutations that contribute to the initial preservation of duplicate genes remain unclear (Lynch and Katju 2004).

Note however, that MS-OPs and MS-RPs not only provide compensation to mutations that have led to their initial recruitment, but also to mutations that occurred later.

(A ) The activity change of mutations that were favorable in the initial stage of reverse evolution, but not reverted.

Such a pattern of changes that involves multiple mutations could be explained by an initial deleterious mutation compensated by selection on subsequent mutations that restored the identity of the S residue.