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We outline the experienced effects and initial merits of the four African NoEs in terms of governance, baseline studies, capacity building, networking, research outputs, and ability to leverage further funding under this newly introduced model.
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Instead the state would adopt a new system of initial merit appointment and nonpartisan retention elections.
Two selenium sites (out of the three possible) were located and gave an initial figure-of-merit of 0.35, which increased to 0.75 after density modification.
All of which suggests Google was perhaps not being so rigorous in assessing the merits of initial requests, in the interests of quickly cutting through the backlog in order to get on top of the process — but has since, perhaps, tightened up its assessments, now it's not facing such a mountain of requests.
What we learn in season five is that institutions aren't concerned with the merits of an initial proposition, that institutions are validated by their responses to the proposition, and also that hierarchies within institutions – including senior public servants – treat institutional responses as opportunities, sometimes as a "career case".
Well, if solely taken on the merits of their initial laurels, neither: Ribonucleotides have yet to be produced under any prebiotic conditions deemed universally reasonable, and, at up to 400°C, black smokers might be too chemically extreme to serve as the biosynthetic cradle of life.
So although we cannot draw any firm conclusions at this stage, we emerge from this effort with a better understanding of the evidence that is available to support the merits of our initial hypothesis (i.e. that low-dose exposures to disruptive chemicals that are not individually carcinogenic may be capable of instigating and/or enabling carcinogenesis).
Crystallographic phases were determined by single wavelength anomalous diffraction methods from data collected on crystals of SeMet CylM to a resolution limit of 2.7 Å. Heavy atom sites were located using the SHELX (Sheldrick, 2010) suite of programs and refinement of heavy atom parameters in SHARP (Bricogne et al., 2003) yielded an initial figure of merit of 0.273.
Phasing by single-wavelength anomalous diffraction was performed using PHENIX.autosol (36), which located and refined 27 iodine atoms to produce a density map with initial figure of merit of 0.51.
Phasing by SAD was performed using PHENIX.autosol (Adams et al., 2002) which located and refined 2 Hg sites to produce a density map with initial figure of merit of 0.39.
Phasing by SAD was performed using PHENIX.autosol (Adams et al., 2002) which located and refined 9 Pb sites to produce a density map with initial figure of merit of 0.36.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com