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Exact(7)
For the Th-17 cells, TGF-β and IL-6 drive the initial lineage commitment.
It is known that HESC do express low baseline levels of lineage-specific markers [28] so when differentiation is triggered by EB formation, the presence of Pax4 or other lineage-specific markers may distort the process of initial lineage selection.
Adipocytes arise from multipotent mesenchymal stem cells (MSCs) through an initial lineage commitment phase, followed by terminal differentiation with accumulation of lipid droplets (Cawthorn et al., 2012).
In the CVTree server, each built-in genome is associated with initial lineage information taken from the NCBI Taxonomy (www.ncbi.nlm.nih.gov/taxonomy ).nih.gov/taxonomy
Fossil occurrences are almost always later than their molecular divergence estimates [ 72, 77], as it is extremely unlikely that fossils capture the moments of initial lineage divergence.
However, any conclusion derived from this approach is confounded by the ancillary question of whether local adaptation to the urban environment predates or arose subsequent to initial lineage splitting between the molecular forms.
Similar(53)
All sequences that did not cluster to form an OG were compiled into an initial lineage-specific gene set.
The genotype of each diploid individual (homozygote or heterozygote) is composed by lineages and is created randomly from a common ancestral pool of lineages (Number of initial lineages A) at the first generation, then from the parental pool of the same deme for all subsequent generations.
In summary, the three models have 12 parameters in common: number of initial lineages in the source population A, selection coefficient s, north-south separation time t 1, as well as independent N, m and r for the NEA, the SEA and the barrier zone.
The CRISPR polymerase domains are highly mobile along with rest of the CRISPR system, though their predominance in archaea might suggest an initial origin in that lineage [ 12, 20, 21].
However, little is known about the relationship between nucleosome dynamics and initial cell lineage specification.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com