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The Heart Protection Study found that statins decreased mortality and major cardiovascular events in high-risk persons regardless of the initial level of serum lipids, age, or gender.
The Heart Protection Study (HPS) showed that statins reduced mortality and major cardiovascular events in high-risk persons regardless of the initial level of serum lipids, age, or gender (HPS 2002).
There was no significant difference in the initial level of serum MMP-3 among patients with short, intermediate or long disease duration [247 (50 ~ 352) ng/ml vs 159 63 ~ 2911) ng/ml vs 279 (41 ~ 440) ng/ml, P = 0.875].
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These significant decreases in mortality and in cardiovascular events occurred regardless of initial levels of serum lipids, age, or gender.
The HPS Investigators recommended treating persons at high risk for cardiovascular events with statins, regardless of the initial levels of serum lipids, age, or gender (HPS 2002).
A simple definition of poor prognosis based on raised initial levels of serum tumour markers alpha fetoprotein (aFP) and human chorionic gonadotrophin (hCG) proved at least as useful (sensitivity 80%, specificity 55%) as other more complicated systems in predicting failure to achieve long-term survival.
Reduction in cholesterol absorption was strongly related to the initial level of absorbed cholesterol tracer in serum (rs=−0.739).
Dissociated spheres re-exposed to serum rapidly expressed initial levels of WT and MU transcripts (Figure 8G).
To correlate the live delivery rate with the initial level and rise of serum β-hCG.
Between 1995 and 1998, the prevention programme focused on two-stage mass screening for gastric neoplasia, with an initial biomarker test (according to the level of serum pepsinogen and H pylori antibody) and subsequent endoscopic examination for positive subjects.
The initial proliferative phase of alveolar morphogenesis is instigated by an increase in the level of serum prolactin (Prl) and progesterone (Pg) [ 1].
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