Based on the Snell's law and the energy conservation law, the front and back freeform surfaces of the initial lens are calculated numerically by solving the corresponding first-order partial differential equations.
As illustrated in Figure 3, initial lens changes appeared ca. 65 days after irradiation as a diffuse posterior subcapsular (PSC) clouding (haze).
Initial lens changes appeared as a diffuse PSC clouding (haze) which progressed to dense PSC opacification and punctate opacities that blocked visualization of the retina.
Compared to untreated, irradiated rats, treatment with pantethine, 4 and 8 delayed initial lens changes by 4, 47, and 38 days, respectively, and the average formation of posterior subcapsular opacities by 23, 53 and 58 days, respectively.
The invagination of these cells establishes the initial lens 3D structure, the lens vesicle, which is composed of lens precursor cells.
In the second phase, the lens placode, which is composed of elongated cells, invaginates to form the lens pit and lens vesicle, which is the initial lens 3D structure.
After initial fixation, lenses were carefully dissected by removing crescent-shaped groups of fibers at successive depths.
To provide guidelines for the selection of an initial contact lens (CL) power based on the preoperative characteristics of the patient in eyes undergoing infantile cataract surgery without primary intraocular lens (IOL) implantation.
For our initial measurements, tube lenses with different magnifications were inserted to optimize field of view (FOV) and optical resolution on a camera that had 9µm square pixels.
