Sentence examples for initial internalization from inspiring English sources

Although these mutants were internalized at a high rate, this increase in initial internalization is not sufficient to explain the hypercytotoxic phenotype.

This effect could be due to a slower and inefficient internalization of the receptor from the plasma membrane to endocytic vesicles, which would leave some receptors at the membrane, and/or to an impairment of vesicle transport after the initial internalization from the membrane.

This scheme is focused on initial internalization of the phage and selection of the internalization pathway.

Specifically, RGD of KSHV gB functionally interacts with integrins α3β1, αVβ3, and αVβ5 that have a role in the initial internalization of the virus [ 5, 7, 14, 35].

Although the initial internalization of aggregated LDL into the SCC was independent of the LDL-receptor, slow LDL receptor-dependent degradation of the internalized LDL was taking place [14].

Notably, a previous study by Schornberg et al. also provides evidence that viruses utilize integrins for regulation of virus entry at steps beyond binding and initial internalization to promote virus penetration from endocytic organelles.

Despite the initial lower internalization level of mutant strain SM001, the proportion of internalized bacteria had a similar doubling time as the wild type W225.

However, we also observed rapid dye unloading by peripheral tubules and smaller vesicles that occurred as early as 20 s after the initial endocytic internalization.

Rather, it concerns only the initial stage of internalization, i.e., when membrane deformation begins to develop.

The finding suggests that CXCR7 expression at the cell surface is tightly regulated and the receptor is rapidly replenished from intracellular stores after an initial agonist-induced internalization.

Thus, the initial imbalance between internalization and reinsertion is small.