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It is based on the Spark framework and covers all the steps required by our approach, starting from the initial indexing of a set of FASTA sequences up to producing a report detailing the distances among these sequences, ranked according to a user-defined measure.
The initial indexing process can take two or more hours, so I recommend you do it while you're away from the PC.
In addition to the original 11-mer index of BLAT [47], EvoPrinterHD indexes each genome into a second set of non-overlapping 11-mers, offset by four base pairs from the initial indexing, and into a third set of non-overlapping 9-mers.
Initial indexing and determination of an optimal data collection strategy was done using Mosflm (Leslie, 2006).
Initial indexing of data on individual patients treated by respondents was undertaken by a non-clinical researcher (GS) and then reviewed and refined by a senior clinician (AB) resulting in consensus about a smaller number of refined, descriptive categories.
In addition to the original non-overlapping 11-mer genomic index of BLAT [ 6], EvoPrinterHD indexes each genome into a second set of non-overlapping 11-mers, offset by four base pairs from the initial indexing, and into a third set of non-overlapping 9-mers.
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With the help of two standard statistical software packages, the reliability and validity of the initialized index system are established, and then the optimization of the initial index system is carried out by means of Factor Analysis.
The key idea underlying our approach is to compress the initial index domain along a number of directions in order to obtain a new domain that is more suitable for the application of projection methods.
Step 6: Set the maximum iteration number as L and its initial index l = 1.
The index will grow over time too as it seeks out further connections by analysing the conversations taking place between its initial index of users and those that they converse with.
The sink node creates an initial index for each cluster, while each CH calculates the index for each of its VCs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com