Sentence examples for initial hits from inspiring English sources

Initial hits bound to GR but lacked agonist activity.

Of these six initial hits, compound 13b6 was the most active.

Of these three initial hits, compound 9a2 was the most potent.

Initial hits were sorted using a number of parameters and finally seven compounds were proposed as potential HIV-protease molecules.

SAR analysis was performed to further improve antiviral potency and to optimize drug-like properties of the initial hits.

The film-survey strategy was successful: 11,336 initial hits on the survey website led to 6944 completed surveys.

Fragment-based drug discovery involves screening simple, low-molecular weight compounds to generate initial hits against a target.

Development of quality leads using hit confirmation and hit-to-lead approaches present their own challenges, depending on the hit discovery method used to identify the initial hits.

With efforts on rigorous validation and expertise, we have identified such pharmacophoric patterns from natural compounds that can be used as initial hits.

After their initial hits, she went off on her own, and the Dudes named their next album "Hamba Uzobuya" ("Yeah, Go, but You'll Come Back").

The overall procedure represents a rational and comprehensive means of evaluating antifungal activity from various perspectives for the selection of initial hits that can be explored in more in-depth mode-of-action studies.