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The initial hint was co-purification of a cAMP-dependent kinase activity with the proteasome complex from bovine pituitaries.
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Figure 1 summarizes how HINT was built.
Here, some initial hints can be inferred from mutational analysis.
HINT is a nonintrusive testbed.
The mechanisms of HINT are shown in Figure 5. Figure 5 The mechanisms of HINT.
A former restaurant manager, he says that at his first home, the initial hint of trouble brewing was the menu: Cheerios for breakfast and hot dogs for dinner, day after day.
In conclusion, our findings are an initial hint that work-family conflicts might be a risk factor for poor work ability in female patients with musculoskeletal disorders.
Despite the severe phenotype of THEMIS-deficient mice and initial hints that THEMIS was implicated in regulating TCR signalling (Fu et al, 2009; Brockmeyer et al, 2011), its precise molecular and functional role has remained obscure.
The initial hint that this daft blather was bordering on pure nuttiness comes from the fact that Joy and Kurzweil talked about these issues at some hotel bar where guys like this gather after attending various group-think functions and conferences.
Furthermore, initial hints that TGs are involved in both bioenergetics and transcriptional dysfunction due to expanded polyQ proteins came from two sets of studies from the same group.
There were initial hints of the flat singing that used to plague her, a faint trace of a wobble in one passage; but over all her vocal performance was magnificent: firm and exciting.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com