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The loci detected with this model were thereafter used as initial factors in a multi-dimensional model in R/qtl.
MBL has been the most studied of the initial factors in the lectin complement pathway [ 14– 18, 20].
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This suggests that loss of T cell function is not the initial factor in development of active TB disease and supports the requirement for biomarkers of TB disease to account for the stage of disease and bacterial load.
Spindle orientation seems to be a key initial factor in acquisition of asymmetric cell fates.
Together, our results suggest that GPR30 interference with the EGFR signaling pathway is an initial factor in development of tamoxifen resistance in breast cancer.
Liver cirrhosis is the initial factor in this mechanism, but one of the key links to endotoxemia formation is the disappearance of intestinal mucosal integrity [ 4- 6].
Inflammation plays a critical role in the development and progression of coronary heart disease (CHD), and increased local inflammation may induce plaque rupture, which has been acknowledged as the initial factor in acute coronary syndrome.
Finally, there are limitations inherent to principal component analysis owing to arbitrary decisions in determining the number of factors to retain, in choosing the method of rotation of the initial factors, and in labeling the dietary patterns (9, 21).
Eigenvalues of initial factors are given in a scree plot [ 21] in Figure 3.
Daverat P, Gagon M, Dartigues JF, Mazaus JM, Barat M. Initial factors predicting survival in patients with a spinal cord injury.
Results suggested that only five out of the six initial factors should be included in the final CFA model (see above).
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