Sentence examples for initial drug loss from inspiring English sources

Such properties could allow drug delivery to the site of action without high initial drug loss.

Many preparation methods have been described and most have been reported to involve a high initial drug loss when introduced in an aqueous environment.

The optimized formulation (F4) showed almost complete drug release in the colon (99.86%) within 24 h without drug loss in the initial lag period of 5 h (only 6.84% drug release was observed during this period).

These receptors, therefore, not only mediate initial drug reward but may also be implicated in further behavioral changes, such as loss of control, that occur in chronic drug abusers.

Although loss of Caspase-2 did not dramatically enhance chemosensitivity per se, it did not hamper initial drug sensitivity or drug sensitivity following repeated doses, despite the fact that Caspase-2-deficient tumors were more advanced than wild-type tumors.

No initial drug burst was observed.

Furthermore, the initial drug content was altered (from 10%to50%0%).

Initial drug therapy, including glucose, oxygen and bicarbonate, is intended to restore metabolic homeostasis.

The final step records a 35% weight loss with the major peak occurs around 827°C (temperature range 680 928°C) which is ascribed to the complete decomposition of amorphous mixture of salts generated during the initial drug decomposition [15].

Higher initial drug feeding was associated with increased drug content in nanoparticles and in nanoparticle size.

Drug-loaded nanoparticles were prepared with initial drug loading of 5% (w/w of PLGA) paclitaxel.