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The dates of treatment initiation and discontinuation, initial dosing, dates and reasons for treatment interruptions and treatment changes, dosing modifications, and follow-up tumor assessments were also recorded.
Other treatment-related data collected included dates of treatment initiation and discontinuation, initial dosing, dates and reasons of treatment interruptions and treatment changes, dosing modifications and follow-up tumor assessments.
For warfarin, genotying is important for initial dosing to avoid adverse events in initiation phase, but this does not supercede the need for therapeutic monitoring of anticoagulation.
The most common initial dosing regimen for gentamicin was 5mg/kg.
Five ICUs (19%) used a higher initial dosing regime of 7mg/kg.
However, there is real potential for delayed complications as the peak BP response may not occur for up to 4 h after initial dosing [19].
The initial dosing (3 days three times monthly) was chosen because of the 7-day persistence of azithromycin in the tears.
Conclusions Although this is a small study, it suggests that esmolol is more effective in converting patients to normal sinus rhythm than diltiazem during the initial dosing period.
Patients subsequently were seen 24 and 48 hours after the initial dosing; intravaginal misoprostol was readministered only if ultrasound images revealed evidence of persistent pregnancy tissue.
An initial bolus of unfractionated heparin ranging from 30 to 85 IU kg was infused and then continued by continuous perfusion with an initial dosing ranging from 15 IU kg h to 215 IU kg h.
Conclusions: Initial dosing of 50 μg/day 12-177 μg/kg per day) raised serum T4 and free T4 concentrations to target range by 3 days and normalized TSH by 2 weeks of therapy.
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