Sentence examples for initial dose levels from inspiring English sources

Patients underwent conversion from previous therapy to 1 of 6 possible initial dose levels, based on individual patient characteristics and generally accepted morphine equivalent conversion factors.

Parallel masitinib-treatment groups at different initial dose levels were studied to determine the optimal starting dose of masitinib, with dose adjustments possible in cases of insufficient response.

For the initial dose levels, an accelerated titration design was used with one patient at each dose (5 mg, 10 mg, 15 mg, 30 mg) treated and evaluated at the end of 3 weeks.

The initial dose level of 5000 mg/Kg was chosen according to the Criteria for Hazard Category 5 in the GHS (Global Harmonization System) [35].

All toxicity data was reported as per the initial dose level.

Based on that previous study, we decided the initial dose level of this study.

Table 2 shows treatment administered and patient disposition by initial dose level.

The initial dose level was sunitinib 25 mg and bortezomib 1.0 mg m−2.

This study was concurrent chemoradiotherapy, and toxicities, such as mucositis, leukocytopenia, neutropenia, were thought to be more severe than induction chemotherapy; therefore, we reduced the initial dose level of docetaxel and 5-FU, and the initial dose level (level 1) was decided to be docetaxel 60 mg m−2 (day 1), cisplatin 70 mg m−2 (day 4) and 5-FU 600 mg m−2 days1 5days 1 5).

However, because of excessive toxicity at this initial dose level, the treatment plan was revised to include lower dose levels of 150 and 250 mg m−2 per week.

In the case of the initial dose level, the doses of nedaplatin and gemcitabine were reduced by 20 and 200 mg m−2, respectively.