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Initial discordance primarily related to classification of secondary diagnoses.
Tapia et al. reported an initial discordance rate of 7.6% in 105 patients whose primary and metastatic lesions had undergone HER2 evaluation by FISH on primary histological and metastatic cytological specimens [ 13].
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Additional evaluation frequently reveals some elements of discordance with the initial assessment at the referring site and may well result in a changed perspective and different parental decisions [10].
Pot banging, booing and swearing make up the chorus of disgruntled Brazilians, frustrated with a government that has been acting in discordance with their initial campaign promises.
[Full text available: www.springerlink.com/content/y584456707031832/fulltext.pdf] According to the classical view of conceptual change, making students aware of their initial conceptions (and of possible discordances between their conceptions and the conceptions of others) is an essential step in learning (Posner et al., 1982).
This number is smaller than the 1000 randomly selected reference panels used to calculate the baseline mean discordance rate in the initial analysis, owing to runtime considerations that arise when performing a large number of imputations using the random panels.
The discordance observed in our initial analysis could be due to more frequent detection of H2O2-nonproducing strains of these species by qPCR, or the L. crispatus and L. jensenii strains that grow well in the laboratory may over-represent those that produce H2O2 compared to the original pool of bacteria.
The rates of staging discordance and the need for change in initial management decisions reported here are very similar to those reported in other studies comparing PET/CT with conventional staging in patients with pancreatic carcinoma.
Of the discordant assays: 1 assay exhibited a single discordance; 2 assays exhibited two discordances and 2 assays exhibited four discordances.
In case of discordance a third, more experienced internist reviewed all documents and the two initial diagnoses and made the final diagnosis.
We analyzed the difference in discordance pattern according to clinical presentation (stage IV vs. recurred) at the time of initial MRCRC diagnosis and metastatic organs from which tissue specimens were obtained.
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