Sentence examples for initial demonstration that from inspiring English sources

Since the initial demonstration that ADPG serves as the precursor molecule for bacterial glycogen biosynthesis, it has been considered that ADPG pyrophosphorylase (GlgC) is the sole enzyme catalyzing the production of ADPG in these organisms.

Over 20 yr after the initial demonstration that DAF-16/FoxO promotes longevity (Kenyon et al. 1993), the question of which DAF-16/FoxO target genes are important for life span extension remains unanswered.

DOI: http://dx.doi.org/10.7554/eLife.00704.002 Since the initial demonstration that mitochondria take up substantial amounts of cytoplasmic Ca2+ (Deluca and Engstrom, 1961), detailed studies have revealed that this uptake can sculpt the cytoplasmic Ca2+ transient (Wheeler et al., 2012), enhance ATP synthesis (Balaban, 2009), and trigger cell death (Zoratti and Szabo, 1995).

A new study led by Lecia Sequist, an instructor at Harvard Medical School and an oncologist at Massachusetts General Hospital Cancer Center, offers an initial demonstration that cancer treatment can be tailored to the genetic profile of a patient's tumor.

After an initial demonstration that normal myoblasts can restore dystrophin expression in mdx mice (Partridge et al. 1989), clinical trials, in which allogeneic normal human myoblasts were injected intramuscularly several times in dystrophic young boys muscles, have not been successful (Law et al. 1990; Mendell et al. 1995).

Since the initial demonstration that these molecular subtypes correlated with differences in survival [ 2], other groups have similarly confirmed the clinical relevance of the biologic subtypes [ 3, 4].

Since our initial demonstrations that hydrogen sulfide (H2S) may function as a neuromodulator in the brain and a smooth muscle relaxant in the vascular system, accumulating evidence shows that H2S may function as a signaling molecule.

Since the initial demonstrations that the CRISPR/Cas9 system could be used for genome editing in C. elegans, several strategies have been used effectively, and significant improvements have been made to facilitate the generation and identification of edited animals.

Government funding should be focused on research and development of new energy technologies and on initial demonstration projects that establish the feasibility of discoveries".

"I think this initial demonstration showed that digital holographic data-storage systems can be built," Hesselink said.

The explosions came two days after thousands of people, some of them coerced, rallied in Damascus in support of Mr. Assad on the anniversary of the initial mass demonstrations that turned sporadic protests against his government into a nationwide movement.