Sentence examples for initial compounds for from inspiring English sources

As previously mentioned, we screened 36 initial compounds for disc sensitivity and MIC, Only the most promising seven compounds were chosen for further testing with the discussed assay.

In the case of electron irradiation, the precipitating bcc phase exhibits preferential crystallographic orientation with respect to the initial compound crystal for irradiation temperatures above 200 K.

We describe the application for EXEG 1706 which was chosen as a representative of 36 initial compounds.

The 6,232 compounds that matched the pharmacophoric features (one HBD, one HBA, and two hydrophobic/aromatic constraints) were enriched from the initial 189,000 compounds for subsequent docking study.

As a pharmaceutical organization, involved in drug discovery, our initial compound libraries are screened for in vitro activity/inhibition assays.

This approach led us to design chemical modifications of the central pyrazole, which solved the poor kinase selectivity seen as a strong liability for the initial compound 1.

But that initial compound is often not suitable for use as a drug because it might not be absorbed into the bloodstream well enough, or it might be chemically unstable, or unsafe.

These qRT-PCR experiments demonstrated a dose-dependent upregulation of SPINK1 alongside a re-evaluation of the candidate genes (KRT17, FBX032, JMJD3) chosen for the initial compound screen.

Paul Herrling, chairman of the Novartis Institute for Tropical Diseases in Singapore, said this was not a case of evergreening because the initial compound was never marketed or intended for market.

We can bring some of the knowledge to their context data and help them look at everything in the drug discovery pipeline from initial compound construction and identification through to pre-clinical trials for failing drug interactions.

Amyris' initial compound was artimesinan, which is the active ingredient to treat malaria in developing countries.