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They changed initial antibiotics in 32% of cases based on infectious diseases consultations [11].
In fact, the major initial antibiotics given to the patients were carbapenem or second-generation cephalosporin.
The number of infections in relation to timing of initial antibiotics and first surgery is shown in Table 1.
We need to know the current status of pathogens and antibiotics therapy for a proper choice of initial antibiotics to improve outcome of the patients.
Too many VAP patients still receive inadequate initial antibiotics even if it is well known that the incidence of MDR pathogen infections is on the rise in ICU.
Studies have suggested that up to 13% of patients receive inappropriate initial antibiotics, which may lead to a worse prognosis [13, 21].
Similar(6)
Secondly, the initial antibiotic therapy in our cohort was varied.
Initial antibiotic regimen prescribed by clinicians was adequate in 107 120 settings (89%, 95% CI [82 94%]).
Previously determined rules to evaluate appropriateness of initial antibiotic therapy have been followed [25, 26].
The initial antibiotic concentration has a remarkable effect on photolytic degradation of tylosin.
Another issue raised by this study is the high rate of inadequate initial antibiotic treatment regimens.
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