Sentence examples for initial alteration from inspiring English sources

As discussed in [17], to accomplish this it is necessary to use an experimental model in which the transformation of a normal, immortalized cell by a single oncogene can be highly controlled, thus permitting the dissection of the sequence of events occuring after the initial alteration and the role of a particular gene or signal transduction pathway.

These aspects are the following ones: 1. Habitability or initial alteration.

This indicates that concentration thresholds occur, below which gene expression levels return to normal after initial alteration.

Patients with a GCS score <15 were considered to have an initial alteration of the level of consciousness.

Some have speculated that initial alteration in basement membrane permeability allows further disruption leading to heightened immune system exposure and development of additional disease [ 9, 21].

All these factors affect neurogenesis in brain regions involved in depression and are functionally interconnected so that initial alteration in one of them results in abnormalities in the others [ 2].

The initial alterations are not well studied due to the lack of a precisely-controlled disease model (Conforti et al., 2007; Kanning et al., 2010).

Initial alterations have included the reestablishment of religious education (banned during the Soviet period) and curriculum changes that have reemphasized the use of the Azerbaijani language and have eliminated ideological content.

Unfortunately, information about initial alterations in cell homing early in the onset of diabetes-induced vascular dysfunction is scarce, as previous studies investigated mainly the late stages of vascular disease, when CPC are dysfunctional and macrovascular damage is already evident.

One candidate promoter (Fam111a) was found to be due to a copy number variation (CNV) and not a methylation change, suggesting initial alterations in the germline epigenome may promote genetic abnormalities such as induced CNV in later generations.

If the residual chrysotile present in cell culture after 8 days of recovery is not sufficient to induce the formation of micronuclei, perhaps all alterations that persist in cell culture after long periods of recovery are a consequence of the initial alterations caused by chrysotile, which remain after subsequent cell divisions and are not the direct action of chrysotile.