The trajectory patterns for two major phases of drug administration, that is, initial natalizumab administration phase versus natalizumab resumption phase were tested separately.
In contrast to WT mice, CCR9−/− animals were unable to regain their initial body weight during the water administration phase (Figure 2B).
Time to initial administration of norepinephrine was calculated from the onset of septic shock to initial norepinephrine administration.
The curves obtained after the p.o. route of administration showed an initial absorption phase with a roughly monoexponential decay after Cmax was reached.
Social scientists reported that in the initial phase the administration, civil society groups and the media kept seeing the disaster as an 'annual flood' which was nothing new for that part of the country [ 28].
For more than 15 years, several strategies to reduce fluid administration in burns during the initial resuscitation phase have been proposed, but no single or simple parameter has shown superiority.
Tumour response was assessed using RECIST version 1.1 at baseline and after the administration of three and six cycles in the initial treatment phase, and every three cycles thereafter in the continuation phase.
We collected the first blood sample 2 hr after IV dose administration; in retrospect, there could have been an initial excretion phase that was not properly captured.
The initial enhancement phase (enhancement within the first 2 3 min after contrast administration) is described as slow, medium, or rapid.
Following intranasal administration, the profiles of nimodipine in brain displayed an initial absorption phase, with maximal concentrations within 30 min, followed by a rapid decline phase for all the three formulations.
However, the administration of HIP could still be a valuable treatment for the initial intraoperative phase and the first weeks post-LT, followed by a switch to other HBIG regimens such as low dose i.m. later on.
