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Some patients with hematologic disorders fail to acquire immune protection by vaccination against Staphylococcus pneumoniae because the underlying severe hematological disease associated with immunosuppression inhibits proper production of immunoglobulins.
After waiting 24 hours for the existing pump proteins (and the mRNA that helps produce them) to degrade, they added a standard chemotherapy agent, called doxorubicin, that inhibits proper DNA replication.
Wing retention is usually caused by poverty or anorexia, for lack of nutrition inhibits proper wing development.
Dickkopf-1 (DKK-1) is a product of OBs that is a potent Wnt pathway inhibitor and inhibits proper differentiation of OBs.
We also examined the effect of tunicamycin (a glycosylation inhibitor that inhibits proper protein folding in ER) on RSC treated with siRNA to test whether the downregulation of Synoviolin increases their susceptibility to apoptosis caused by disruption of ER function.
This is because inflammation of the bowel wall inhibits proper digestion resulting in diarrhea.
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Mutations in the SCN4A gene impede the passage of sodium ions through the cell membrane, inhibiting proper muscle function.
These limitations inhibit proper visualization of the highly compact and detailed cerebellar foliations.
In turn, Article 177 gives national courts a means of "removing the obstacles which inhibit proper application of Community law within the national framework," by enabling them to ask for official interpretations of unfamiliar but relevant laws.
Muslim dismay at Tony Blair's co-invasion of Iraq in 2003 did not sway that decision, though it could be argued that anti-war sentiment inhibited proper post-invasion occupation planning and encouraged the Sunni insurrection against both invaders and Shia Muslims.
Moreover, as primary cilia suppress Hh pathway activation in chondrosarcoma, cellular mechanisms inhibiting proper cilia function may be important in maintaining the neoplastic phenotype.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com