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Inhibition of the mitochondrial respiratory function inhibits progression to G1 in parallel with a reduction in cellular ATP (Sweet and Singh, 1995).
The conclusion made from this trial is that sorafenib inhibits progression of disease independent of KRAS mutational status with no statistical differences when looking at either PFS or OS [31].
Low-dose Hydralazine induces endogenous Tet3-dependent de-methylation and inhibits progression of kidney fibrosis.
Abatacept has a sustained effect that inhibits progression of structural damage.
These findings clearly demonstrate that EFNL not only inhibits progression of established mammary tumors but also reduces mammary tumor multiplicity.
CLA both inhibits progression (Lee et al, 1994) and induces regression (Toomey et al, 2006) of atherosclerosis in animal models.
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Earlier we showed that immunization with BmAFII (Sephadex G-200 eluted) fraction of human lymphatic filaria Brugia malayi inhibited progression of Leishmania donovani infection in golden hamsters.
For example, the steric block at the 5' junction might inhibit initiation whereas the steric block downstream at the 3' junction might inhibit progression.
We provide evidence that STC1 sensitized the cells to ATP upstream of PLC, and that blocking endogenous STC1 using a neutralizing antibody inhibited progression of the calcium wave.
Weekly intra-articular injections of BMP-7 inhibited progression of osteoarthritis.
The SERMs also inhibited progression to invasive carcinoma.
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