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Overexpression of this peptide in target tissues therefore competitively inhibits entry of the Plasmodium parasite.
The exogenous expression of TEX14 inhibits entry of ALIX into the midbody resulting in the formation of several interconnected somatic cells because of failure to complete cytokinesis.
Nevertheless, the observation that dynasore inhibits entry of BTV-1 into BHK cells shows that the entry mechanism is dynamin dependent.
This deletion results in a nonfunctional receptor that inhibits entry of HIV into white blood cells.
57 The bicyclam AMD3100 binds selectively to the CXCR4 coreceptor and inhibits entry of T-tropic HIV-1 and HIV-2.
Purified domain III from DENV-1 and DENV-2 inhibits entry of these serotypes into human HepG2 and mosquito C6/36 cells [ 97].
Similar(51)
Also, both chlorpromazine and Bafilomycin A1 inhibited entry of infectious EBOV.
Therefore, inhibiting entry of pyruvate into mitochondria is a promising strategy for cancer chemotherapy47,50,51. Based on these points of view, we suppose that the novel LDHA inhibitor, PSTMB, can be a potent candidate for development of anti-cancer therapeutic agents.
Indeed, silencing AAK1 and GAK expression inhibited entry of pseudoparticles and cell culture grown-HCV and internalization of Dil-labeled HCV particles with no effect on HCV attachment or RNA replication.
Cell cycle analysis showed that MS4a4B regulated T cell proliferation by inhibiting entry of the cells into S-G2/M phase.
Remarkably, bafilomycin A1 inhibited entry of VACV in S2 cells by 99% and was still 95% below the control after exposure to pH 5 buffer (Fig. 3C), suggesting that entry occurred predominantly or exclusively through a low pH endosomal route.
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