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This chapter provides an overview of major corrosion testing and analysis techniques and their applications in corrosion inhibitor research, with a particular focus on electrochemical evaluation of corrosion protection by rare earth metal (REM) compounds.
Tools that can successfully link the diverse information regarding target sequence, structure, and ligand binding properties now accompany a transformation of protein kinase inhibitor research, away from single, block-buster drug models, and toward "personalized medicine" with niche applications and highly specialized research groups.
Inhibitor research is needed to characterize inhibitor testing among current providers, describe inhibitor characteristics and clinical outcomes, identify key genetic and environmental risk factors, and determine patient health information needs regarding inhibitors.
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Meuth calls PARP-inhibitor research a "graveyard of investigators," but Meuth indulged his ambitious postdoc.
A lead compound A was identified previously as an stearoyl coenzyme A desaturase (SCD) inhibitor during research on potential treatments for obesity.
The role of siglecs and galectins in a range of disease processes such as inflammation, apoptosis and cancer progression has also inspired significant structure-based inhibitor design research.
Not only are SERCA inhibitors valuable research tools, but they also have potential medicinal value as agents against prostate cancer.
The key challenge in the design of kinase inhibitors for research or drug development has been to achieve target specificity.
Here we delineate background, clinical application and drug development of aromatic diamidines that could facilitate the screening for selective ASIC inhibitors for research purposes.
Consequently, in order to reduce time and cost, in addition to design and identify more potent PIM inhibitors, theoretical research can circumvent these difficulties and allow obtaining precise data while taking advantage of the rapid progress of computing chemical descriptors, which can be obtained easily from publicly available software and servers.
Hence, in order to reduce time and cost also, to design more potent PIM inhibitors, theoretical research can circumvent these difficulties and allow obtaining precise data while taking advantage of the rapid progress of computing chemical descriptors, which can be obtained easily from publicly available software and servers.
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