Sentence examples for inhibitor combination from inspiring English sources
In the clinical setting, the majority of PARP inhibitor combination trials have focused upon combining PARP inhibitors with standard of care therapies [reviewed in (Lord & Ashworth, 2012)].
Introduction: Piperacillin/tazobactam (PTZ) is a β-lactam-β-lactamase inhibitor combination with a broad spectrum of antibacterial activity.
In this study, various mechanisms suggestive of oxaliplatin and its MDM2 inhibitor combination were investigated using systems science.
This effect is observed especially in the cases when the same inhibitor combination does not show synergy on the uncoupled single Zn and Fe metals.
The inhibitor-induced RTK profile suggested a kinase inhibitor combination therapy that produced GEMM tumor apoptosis and regression where single agents were ineffective.
Both doses of the calcium antagonist/ACE inhibitor combination therapy lowered diastolic pressure as much as the high dose and significantly better than the lower dose of calcium antagonist monotherapy (with either nifedipine or amlodipine).
The molar proportion of acetate in the inhibitor combination groups was decreased by 6.6 12.5% while those of propionate and butyrate were increased by 7.0 19.2 and 21.9 56.5% (P<0.01), respectively.
No study has investigated the effects of a combination of an angiotensin receptor blocker/calcium channel blocker compared to those of a calcium channel blocker/angiotensin-converting enzyme inhibitor combination.
Similarly, an initial response was followed by re-emergence of resistance following treatment with the IGFR-mTOR inhibitor combination.
Consistent with this interpretation, the observed enhanced sensitivity to Dxr/elongation inhibitor combination was also associated with elevated PARP cleavage (Fig. 1D).
In patient 2, upregulation of mTOR was seen in the primary tumor, perhaps explaining the initial response to the IGF1R and mTOR inhibitor combination, while the resistant tumor that emerged showed activation of the ERK pathway as well.
