Sentence examples for inhibition aging from inspiring English sources

In addition, the basic kinetic constants of inhibition, aging, spontaneous- and oxime-induced-reactivation of erythrocyte AChE from these species were determined with a standard static model.

These findings provoked the present in vitro study which was designed to determine the inhibition, aging, spontaneous and oxime-induced reactivation kinetics of the pesticide paraoxon, serving as a model compound for diethyl-OP, and the oximes obidoxime, pralidoxime, HI 6 and MMB-4 with human, Rhesus monkey, swine, rabbit, rat and guinea pig erythrocyte AChE.

The results of the present study underline the necessity to determine the inhibition, aging and reactivation kinetics in vitro as a basis for the development of meaningful therapeutic animal models, for the proper assessment of in vivo animal data and for the extrapolation of animal data to humans.

We also confirm that MDL-1 inhibits aging, consistent with the observed association between tumor suppressors and inhibition of aging [ 53, 54].

The impact of HIF1 α inhibition, age, Gleason score, and PSA at the time of starting ADT on outcomes was assessed using Cox proportional hazards regression.

Certain 'anticancer drugs' are potential 'anti-aging drugs', and -- vice versa -- inhibition of aging pathways are a strategy to prevent cancer [ 58].

The model is based on a combination of enzyme kinetics (inhibition, reactivation, aging) of AChE with OP, toxicokinetics and oxime pharmacokinetics.

A computer simulation based on combination of AChE kinetic data (inhibition, reactivation, aging) with OP toxicokinetics and oxime pharmacokinetics allows the calculation of AChE activities at different scenarios and may facilitate to define effective oxime concentrations and to optimize oxime dosage in OP poisoning.

But inhibition of aging (and delaying diseases) is not the only way to extend life span.

In mammals, the relationship between autophagy inhibition and aging is still largely phenomenological and correlative.

Observations of a positive effect of dapsone on lifespan in the Caenorhabditis elegans model raise new questions concerning the inhibition of ageing effects of the sulfone in mammalian cells and organisms.