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As investigated elsewhere, the theoretical basis for the topography's function is its ability to create a stable non-wetting state where air pockets at key points in the microscopic features are maintained, thereby inhibiting interaction of microbes with the surface [41].
Within the framework of the study, it has been possible to identify four factors inhibiting interaction, each of which has implications for the applicability of the triple helix approach to the transformation of a science and technology park into a science city through residential development.
In the pipe-lattice model, the default (wild type) setting for each valve is either on or off, reflecting whether the modelled biological interaction represents a facilitating or inhibiting interaction, respectively.
Phosphorylation at tyrosine 892 within the PPxY motif can regulate c-Src interactions with beta-dystroglycan, as well as inhibiting interaction with WW domains.
Thus, anti-IL-6 receptor antibody could be a novel therapeutic agent capable of inhibiting interaction between colon tumours and adjacent stroma.
TNF α and IL-6, as pivotal factors for myeloma, can be ideal targets for therapeutic purpose, either directly or by inhibiting interaction with BMSCs.
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Studies in Arabidopsis and rice indicated that the different SPX domain proteins interact with each other, forming a regulatory network depending on activating and inhibiting interactions [ 96, 98].
Consideration of protein length may be a valuable tool in drug design, one that predicts different strategies for inhibiting interactions in aberrant and normal pathways.
This data suggest that decreasing the single-stranded RNA extension length decreases the affinity to Rnt1p perhaps by inhibiting interactions fostered by deleted sequences.
Networks are represented as directed cyclic graphs with distinct edge types for activating and inhibiting interactions.
These edges are usually labeled with a plus or minus sign for activating or inhibiting interactions, respectively.
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