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LKB1 is phosphorylated on several sites, either activating or inhibiting, by several kinases, including p90 ribosomal S6 kinase (RSK), protein kinase A (PKA), or ataxia-telengiectasia-mutated (ATM) kinase.
Therefore, discovering the pivotal step in RANKL expression may lead to a new insight into periodontal pathogenesis and the development of a new target for periodontal therapy; for example, we can prevent periodontal bone resorption through RANKL expression inhibiting by moderating lymphocytes' function or changing some cytokines' level.
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As for adenovirus production with this cell line, the limitations in viral productivity beyond a critical cell density could be related to either nutrient limitations or inhibiting by-product concentrations [ 13, 14].
She was inhibited by not knowing guitar.
Millwall's progress has been inhibited by injuries.
Perhaps the press was also inhibited by its own failures.
Far too many women, she thinks, are inhibited by fear.
The women, inhibited by family pressures, are generally left behind.
8. Don't be inhibited by the language barrier.
Directed by Randy Skinner, the production is not inhibited by its concert format.
Any move to make their discoveries public were inhibited by fear of retribution, he added.
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